Gulf War Illness (GWI) is a rare disease diagnosed in US Desert Storm veterans due to their exposures to toxins during their deployment. Due to the rarity and idiosyncratic nature of GWI, it is underdiagnosed and patients have been historically difficult to recruit for clinical trials.
We partnered with a major research center within the Mount Sinai Hospital system in New York City. They had received a grant from the Department of Defense to study a treatment for GWI-related pain. 2 years into the recruitment phase of the trial, they had only enrolled 20 patients, 25% of their goal. The grant had been extended twice and was in danger of cancellation.